Detection of neurological damage during cardiopulmonary bypass
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چکیده
منابع مشابه
Hypoxaemia during cardiopulmonary bypass.
For cardiopulmonary bypass during open-heart surgery we use a bubble oxygenator and a technique of haemodilution and moderate hypothermia. During the course of routine perfusion we have observed arterial desaturation in a number of patients and in five patients the desaturation was marked (SaO2<85%)'. The low arterial oxygen saturations occurred mainly in the rewarming period. This report is of...
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The objective of this study was to investigate whether hypertonic hyperosmolar primes solution (HHPS), with an osmolarity of 2300 mOsmol/L, causes endothelial damage/loss. The bodies' normal osmolarity is -280 mOsmol/L. Aortic endothelial cells were cultured and plated to confluence, confirmed by light microscopy, on a 96-well plate. Serial dilutions of HHPS (n = 10) were incubated with the cel...
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Particulate microembolization during extracorporeal circulation is thought to contribute to cerebral, pulmonary and other post-operative complications following cardiac surgical procedures. 11° Factors which have been implicated in microembolic phenomena during cardiopulmonary bypass include: 1 ) transfusion of stored blood ,I· 2 ' '· 11 ' ' 3 22 2) formation of platelet aggregates in the patie...
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Recently, Boisclair et all has given us an important clue to show the main trigger to coagulation activity during cardiopulmonary bypass (CPB). They observed the increase of factor IX activation peptide during CPB, which shows a strong correlation with the increase of prothrombin fragment F1 + 2. In contrast, they found no significant increase in factor XIIa levels during CPB. This activation p...
متن کاملPupil changes during cardiopulmonary bypass.
Pupil diameter is used during anaesthesia to assess depth of anaesthesia and indicate cerebral hypoxia. This is especially so during cardiac bypass when other autonomic signs cannot be monitored. We have used a pupillometer to determine the effect of cardiopulmonary bypass on the pupil. We have also investigated if any effect was caused by washout of opioid from the central nervous system by al...
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ژورنال
عنوان ژورنال: Anaesthesia
سال: 1986
ISSN: 0003-2409,1365-2044
DOI: 10.1111/j.1365-2044.1986.tb12706.x